As I've been preparing for a talk in Manchester on Blake and comics, entitled "Here be Tygers", I thought I'd share this little oddity from Marvel Comics. Part of the Marvel Team-Up series, Spider-Man and Tigra: At Kraven's Command! is probably the oldest comic I have with a Blake connection as it was published in 1978.
Written by Chris Claremont with art by Dave Hunt and John Byrne among others, the Blake connection is pretty slender, to be honest. On the inside cover, Peter Parker is shown spinning his flight between buildings, worrying that he should really be studying but enjoying the freedom that his spidey-skills bring. Above him in bold letters reads the heading: "Tigra Tigra Burning Bright!"
It's the oldest direct comic book reference I've found so far (and I'd be very happy to be contradicted/enlightened/educated in the comments below!) The story itself is usual Marvel fare from the seventies: Spider-Man, seeking to capture his foe Kraven the Hunter is himself caught and taken to Kraven's lair. There the hunter sets Tigra - formerly an ally of the Fantastic Four but now controlled by an electronic collar that makes her Kraven's slave - on Parker, an act that will result in his or her death that is (of course) averted when he uses his strength to destroy the collar.
As far as Blakeana goes, it is an extremely superficial link, more useful in many respects as an indication of just how prevalent the poem "The Tyger" was in post-war pop culture that Marvel could reference it in a pun with absolutely no further reference and expect its audience to get the joke. I'll follow with a couple more from the collection at a later date.